L-蘇糖酸鎂(Magnesium-L-threonate)對人體睡眠的影響

L-蘇糖酸作為維生素C的降解產物，能夠促進維生素C的吸收和利用，從而提高其活性，且與胰島素有協同作用，作為金屬離子的載體可使金屬離子易與氨基酸或蛋白質結合而被動物吸收和利用，在人體中具有較高的生理活性。鎂可通過抑制Na⁺-K⁺-ATP酶及鎂-ATP酶，調節中樞神經遞質如兒茶酚胺、阿片受體及神經DNA受體影響中樞神經功能及激素對神經功能的調節。由于腦脊液內鎂離子含量高于血漿，因此單純給予常用的鎂鹽如MgSO₄或MgCl₂，對于腦內鎂離子含量的提高作用甚微。L-蘇糖酸鎂具有很高的生物利用度，通過飲食補給L-蘇糖酸鎂可以顯著的升高腦內的鎂離子水平，通過提高腦鎂可以增強大鼠的長短期記憶力，可以防止和恢復記憶缺陷，改善了學習和記憶功能；治療精神分裂癥，對突觸有保護作用，可能具有治療阿爾茨海默氏病的潛力。γ-氨基丁酸是哺乳動物中樞神經系統內最重要的氨基酸類神經遞質，對神經元的活動具有抑制作用，在睡眠的調節中發揮著重要的作用，γ-氨基丁酸有促進睡眠的生理功能。Mg²⁺可增強γ-氨基丁酸誘發的電流，通過正性變構調節機制影響 γ-氨基丁酸 A 型受體的功能。 在本實驗中 L-蘇糖酸鎂本身無催眠作用，但與巴比妥類共同作用，一定條件下能改善睡眠。

公司官網：www.wilincare.net歡迎選購！

氨基酸螯合鈣Amino acid chelate calcium、抗壞血酸錳Manganese Ascorbate、、賴氨酸甘氨酸鎂Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺鎂Magnesium Glycinate Glutamine、檸檬酸蘋果酸鎂Magnesium Citrate Malate、檸檬酸鍶Strontium Citrate、檸檬酸錳Manganese Citrate、檸檬酸銅Copper Citrate、天門冬氨酸鋰Lithium Aspartate、牛磺酸硒Selenium Taurate

Effects of Magnesium L-threonate on sleep

L-threonic acid, as a degradation product of vitamin C, can promote the absorption and utilization of vitamin C, thereby improving its activity, and has a synergistic effect with insulin. As a carrier of metal ions, metal ions can be easily combined with amino acids or proteins and be absorbed and utilized by animals, and has a high physiological activity in the human body. By inhibiting Na⁺-K⁺-ATPase and magnesium-ATPase, magnesium can regulate central neurotransmitters such as catecholamines, opioid receptors and nerve DNA receptors to affect central nervous function and hormone regulation of nerve function. Since the content of magnesium ions in cerebrospinal fluid is higher than that in plasma, the simple administration of commonly used magnesium salts such as MgSO₄ or MgCl₂ has little effect on the increase of magnesium ion content in brain. Magnesium L-threonate has a high bioavailability. Dietary supplementation of magnesium L-threonate can significantly increase the level of magnesium ion in the brain, enhance the short and long term memory of rats, prevent and restore memory defects, and improve learning and memory functions. Treating schizophrenia, which has a protective effect on synapses, may have potential to treat Alzheimer's disease. Gamma-aminobutyric acid (GAMma-aminobutyric acid) is the most important amino acid neurotransmitter in the central nervous system of mammals. It has inhibitory effect on the activity of neurons and plays an important role in the regulation of sleep. Gamma-aminobutyric acid has the physiological function of promoting sleep. Mg²⁺ can enhance the current induced by gamma-aminobutyric acid and affect the function of gamma-aminobutyric acid type A receptor through positive allosteric regulatory mechanisms. In this experiment, magnesium L-threonate itself has no hypnotic effect, but it can improve sleep under certain conditions by interacting with barbiturates.

Company's official website: www.wilincare.net welcome to buy!

Amino acid chelate calcium, Manganese Ascorbate, Magnesium Lysinate Glycinate, Magnesium lysinate glycinate, magnesium glutamine Glycinate Glutamine, Magnesium Citrate Malate, Strontium Citrate, Manganese Citrate, Copper citrate Citrate, Lithium Aspartate, Selenium Taurate.